While most doctors maintain that ingredients shouldn’t be trendy (because what works, works), the beauty industry can’t help but get caught up in what’s popular. Tranexamic acid and ceramides are having a moment right now, but we’re looking ahead. We asked our experts which skin-care ingredients they predict will be big in 2025. Hint: it’s all about regenerative benefits and targeted treatments.
Featured Experts
- Julie Russak, MD is a board-certified dermatologist based in New York
- Kathleen Behr, MD is a board-certified dermatologist based in Fresno, CA
- Kally Papantoniou, MD is a board-certified dermatologist based in New York
- Sue Ellen Cox, MD is a board-certified dermatologist based in Chapel Hill, NC
Peptides
New York dermatologist Julie Russak, MD projects that peptides, already beloved for its versatility, will stay at the forefront. “These amino acid chains signal the skin to boost collagen and repair the barrier,” she explains. From lip treatments to moisturizers, we’ve been seeing this ingredient front and center on a handful of products recently.
“We’ll likely see more advanced peptide products in 2025, with new complexes targeting specific skin issues like lifting and firming,” says Dr. Russak. “Matrixyl and copper peptides have already proven their worth, but newer formulations will offer even more precise benefits for both the face and body.”
Products to try: Alpyn Barrier Repair Cream ($62), Rhode Peptide Glazing Fluid ($30), Naturium Multi-Peptide Advanced Serum ($25), Allies of Skin Peptides & Antioxidants Firming Daily Treatment ($88)
Exosomes
Both Dr. Russak and Fresno, CA dermatologist Kathleen Behr, MD predict exosomes will continue to grow in popularity in 2025. “Exosomes help repair and regenerate damaged skin cells to reduce wrinkles and promote radiant skin,” explains Dr. Behr. Who doesn’t want that? Exosome technology continues to advance, making it more common in formulas.
“Exosomes, tiny vesicles from stem cells, play a key role in cell-to-cell communication, delivering growth factors and proteins directly where they’re needed. Exosomes are becoming a focus in dermatology and regenerative aesthetics, especially for their role in wound healing, post-care, collagen production and skin repair,” says Dr. Russak. “As research backs their efficacy, I expect exosomes to be a game-changer in anti-aging treatments and regenerating and repairing damaged or aging skin.”
Products to try: SkinMedica TNS+ Recovery Complex ($230), Plated Intense Serum ($258) ShapeShift V-Line Jaw Defining Serum ($58), Beekman 1802 Milk RX Advanced Better Aging Cream ($66)
Niacinamide
Niacinamide is nothing new—New York dermatologist Kally Papantoniou, MD says it will always remain a key player when it comes to calming, anti-inflammatory skin care—but this year, its star will shine even brighter. “Its ability to improve skin texture, minimize the appearance of pores and strengthen the skin barrier makes it a go-to ingredient for those looking for both prevention and correction in their routines,” she says.
Products to try: Beautypie Superdrops ($38), La Roche-Posay Mela B3 Serum ($45), Sunday Riley B3 Nice ($62), Kiehl’s Ultra Pure High-Potency Serum ($35)
Probiotics
“In 2025, I anticipate that skin-care companies will continue to prioritize the health of the microbiome. In recent product launches, we’ve seen the use of probiotics to help support the microorganisms and bacteria that reside there,” says Chapel Hill, NC dermatologist Sue Ellen Cox, MD. “As our understanding of the microbiome deepens, I expect to see even more creative applications of probiotics in skin care.”
Products to try: BeautyStat Universal Pro-Bio Moisture Boost Cream ($31), Nuebiome Empris-Peony Biotic Resurfacing Night Serum ($75), Epicuren Acidophilus Probiotic Facial Cream ($64), Coola Dew Good Illuminating Serum ($48)
Natural Oils
Dr. Papntoniou foresees natural oils growing in popularity “due to their ability to support the skin barrier, provide hydration and offer anti-inflammatory and antioxidant benefits. Their lightweight nature and compatibility with a variety of skin types, along with the demand for clean, sustainable ingredients, make them an appealing choice for both consumers and formulators.”
Products to try: REN Clean Skincare Evercalm Barrier Support Elixir ($59), Oak Essentials Ritual Oil ($88), Farmacy Honey Grail ($49), Youth To The People Superberry Hydrating Face Oil ($49)
Antioxidants
“I think we’ll see a continued emphasis on advanced antioxidants, which are crucial for protecting the skin from environmental damage and oxidative stress. Ingredients like vitamins C and E, which are already staples, will likely remain popular as people increasingly seek out products that not only address signs of aging but also protect against future damage,” says Dr. Papantoniou. “These ingredients are becoming essential for anyone focused on maintaining vibrant, healthy skin for the long term.”
Products to try: Alastin Skincare C-Radical Defense ($211), 111 Skin Antioxidant Essence NAC Y² ($105), Tatcha Violet-C Brightening Serum ($89), Paula’s Choice Super Antioxidant Serum ($45)
